The triac distal ring is well defined and makes hydrophobic contacts with a deep af 2 subpocket s1 that hosts f 1 or l 1 of the signature motif f 1 xxl 4 f 5 l 1 xxl 4 l 5 but the proximal phenyl ring is poorly defined and spans the s2 and s3 subsites that host l 4 and f 5 l 5 fig.
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Knockdown of genes involved in axonal transport enhances the toxicity of human neuromuscular disease linked matr3 mutations in drosophila febs lett 2020 june pmid.
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Sp le k che lutz k chen prospekte xxl lutz splbecken images below is section of lutz kücheninsel piece of writing which is labeled within ideas and posted at october 12 2019.
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Mcoln1 possesses a de xxxl li motif near its n terminus eterll and its c terminus eehsll.
Nef induced cd4 and major histocompatibility complex class i mhc i down regulation are governed by distinct determinants.
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Right approximately 24 h after repetitive spaced odor blue light isi 15 sec or blue light odor isi 80 sec training the scores of mb320c chop2 xxl flies did not differ from those of the genetic controls suggesting complete decay of both kinds of memory established the day before u tests.
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The limiting membrane of lysosomes in animal cells and that of the vacuole in yeast include a wide variety of transporters but little is known about how these proteins reach their destination.
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Reported that loss of the c terminal dileucine motif of mcoln1 resulted in loss of lysosomal targeting and accumulation at the pm 23 others have demonstrated that mutation of both the n and c terminal dileucine motifs are needed to disrupt the lysosomal targeting of.
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